Expression of myeloma cell BCMA and soluble BCMA in relapsed and refractory multiple myeloma subjects treated with GSK2857916 in BMA117159, 4. INTREPID: Clinical Effectiveness of Once-Daily Single-Inhaler Fluticasone Furoate/Umeclidinium/Vilanterol Versus Multiple-Inhaler Triple Therapy in Usual Clinical Practice. Impact of the COVID-19 Pandemic on Health Care Resource Utilization (HCRU) and Costs in Chronic Obstructive Pulmonary Disease (COPD) in the United States: A Population-Based Study. Montes de Oca R, Bhattacharya S, Vitali N, et al. Niraparib is a selective PARP1/2 inhibitor approved as monotherapy for the maintenance treatment of adult patients with recurrent ovarian, fallopian tube, or primary peritoneal cancer who are in response (complete or partial) to platinum-based chemotherapy. Asthma Control in Patients With Severe Eosinophilic Asthma Treated With Mepolizumab in Real-Life Settings: The Prospective, REALITI-A Study. Prevalence of asthma and severe asthma in patients affiliated to the Hospital Italiano Medical Care Program in Buenos Aires, Argentina. PO1437, 2. Comparative Efficacy of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Versus Other Triple Therapies for the Treatment of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review and Network Meta-Analysis. Association between TGF-? 2. Rapoport AP, Stadtmauer EA, Binder-Scholl GK, et al. 1. Silver J, Deb A, Packnett E, et al 2017;276(1):80-96. PLAIN LANGUAGE SUMMARY [HCP USE ONLY]: The DREAMM-6 Study: What Side Effects Were Experienced When Patients With Multiple Myeloma Were Treated With Belantamab Mafodotin in Combination With Another Anti-Myeloma Treatment, Bortezomib/Dexamethasone? ENCORE: Safety and activity of autologous T cells with enhanced NY-ESO-1?specific T-cell receptor (GSK3377794) in HLA-a*02+ previously-treated and -untreated patients with advanced metastatic/unresectable synovial sarcoma: A master protocol study design (IGNYTE-E), 19. POSTER: Efficacy of dostarlimab in endometrial cancer by molecular subtype: a post hoc analysis of the GARNET study (ESMO ENCORE), 10. Front Oncol. Encore: DREAMM-9: Phase III Study of Belantamab Mafodotin Plus VRd vs. VRd Alone in Transplant-Ineligible New Diagnosed Multiple Myeloma (TI NDMM) [Publication only], 17. Hemoglobin Efficacy and Cardiovascular Safety Data from the ASCEND-ND, -D, and -ID Trials. Analysis of a Composite Endpoint of Exacerbation and Early Study Treatment Withdrawal in Symptomatic Patients With COPD Free of Inhaled Corticosteroids: A Post Hoc Analysis of the EMAX Trial. 5. ?Trap?/Anti-PD-L1 Fusion Protein, Belantamab Mafodotin - Anti-BCMA Immunoconjugate, PRMT5 Inhibitor (GSK3326595) and Type I PRMT Inhibitor (GSK3368715). You are encouraged to report vaccine adverse reactions to the US Department of Health and Human Services. Corbridge T, Deb A, Packnett E, et al. GSK6097608 inhibits the binding of CD96 to CD155 and activates T cells and NK cells, which enhances antitumor activity. Moretz C, Hahn B, White J, et al. April 27, 2023. Real-World Treatment Patterns Following Chronic Obstructive Pulmonary Disease (COPD) Exacerbation in Patients with Commercial or Medicare Insurance in the U.S. 5. [Poster No. Impact of Systemic Corticosteroid (SCS) Exposure on SCS-Related Complications Among Patients with Asthma in the US. 1053; Abstract A5058]. GSK. National Differences in Real-World Outcomes with Mepolizumab Treatment for Patients with Severe Asthma: Results from the REALITI-A Study. P1481. Phase 2 study of bintrafusp alfa, a bifunctional fusion protein targeting TGF-? Trade marks are owned by or licensed to the GSK group of companies. Maximal Change in Erythropoietin in Hemodialysis ?Patients Receiving Daprodustat or Epoetin Alfa ?in the ASCEND-TD Trial, 9. 1. CD8?-enhanced NY-ESO-1-Specific TCR T Cells (GSK3901961) in HLA-A*02 Patients with NSCLC: Master Protocol Substudy 1, 1.ORAL PRESENTATION:DREAMM-6: Safety and Tolerability of Belantamab Mafodotin in Combination with Bortezomib/Dexamethasone in Relapsed/Refractory Multiple Myeloma (RRMM). POSTER: Immuno-PET monitoring of CD8 + T cell infiltration post anti-ICOS agonist antibody treatment alone and in combination with PD-1 blocking antibody using a 89Zr anti-CD8+ mouse minibody in EMT 6 syngeneic tumor mouse, 4. Please help us protect Glassdoor by verifying that you're a Time-Dependent Covariate Analysis of Hemoglobin Values ?on Risk of MACE in the ASCEND Trials. 3. A prospective evaluation of tolerability of niraparib dosing based upon baseline body weight and platelet count: blinded pooled interim safety data from the PRIMA/ENGOT-OV26/GOGO3012 Study, 6. The PLUTO study: intravenous belimumab in children with systemic lupus erythematosus, 3. Asthma control among the treated U.S. asthma population in Practice Fusion?s Electronic Medical Record Research Database, 2015-2018. 37 GSK Global Medical Affairs Lead jobs. 4. Chaudhuri R, Canonica GW, Bals R, et al. In early stages, ~1/3 of people with the disease may not have any, but as it progresses, patients may experience a variety of symptoms that differ from person-to-person. We expect our organization to represent the population we serve by leveraging qualified, talented individuals who represent a variety of ethnicities, genders, disabilities, ages and sexual orientations. POSTER: Cytochrome P450 inhibiting/inducing medication use among patients with advanced ovarian cancer who receive or are eligible for poly (ADP-ribose) polymerase inhibitors as first-line maintenance therapy, 1. P786; Abstract A5624]. 1. We support smart risk-taking while doing the right thing, invest in innovation where and when it matters, and constantly strive to do things better to make an impact on peoples health across the world. and Physicians? Find out more: gsk.to/41zwzb7, While everyone can be impacted by #myelofibrosis, certain risk factors can increase the likelihood that a person will develop it. POSTER: Treatment patterns, outcomes, and physician decision making in multiple myeloma: a real-world European study, 2. Sci Transl Med. Rationale for anti-OX40 cancer immunotherapy. Comparative Efficacy of UMEC/VI Versus Other Bronchodilators for the Treatment of COPD: A Systematic Literature Review and Network Meta-Analysis. Disculpa and PD-L1 pathways. On-Treatment Cancer Safety Events with Daprodustat Versus Erythropoiesis-Stimulating Agents ? in Patients with Asthma: A Post-Marketing Surveillance (PMS) in Korea. Int J Mol Sci. ORAL PRESENTATION: MOMENTUM: Phase 3 Randomized Study of Momelotinib (MB) versus Danazol (DAN) in Symptomatic and Anemia Myelofibrosis (MF) Patients Previously Treated with a JAK Inhibitor, 2. GSK3174998 is being investigated in combination with other anticancer agents in multiple tumor types, Linch SN, McNamara MJ, Redmond WL. PO0487, Psychometric Properties of the SF-36 Vitality Scale ?in Patients With Anemia of Chronic Kidney Disease. Exacerbation Reduction in Patients Based Upon Baseline Eosinophil Counts and FEV1 Reversibility. The results included enhanced training for recruiting managers, a thorough review of job postings and more direction on the channels used to reach and attract candidates. Patient-Reported Experience of Eosinophil-Driven Diseases on Online Platforms: Social Listening Analysis Insights. Front Immunol. 2018;22(6):527-545. Encore: Open-label Pilot Study of Genetically Engineered NY-ESO-1?Specific T Cells (GSK3377794) Alone or in Combination With Pembrolizumab in Relapsed/Refractory Multiple Myeloma [Publication only], Pilot Neoadjuvant Study of Niraparib in HER2-Negative, BRCA-Mutated Resectable Breast Cancer, 1. Poster No. Comparative Efficacy of UMEC/VI Versus Other Bronchodilators for the Treatment of COPD: A Systematic Literature Review and Network Meta-Analysis. [Poster No. 4. (Poster No. POSTER: Adoption of New First-line Maintenance Strategies Among Patients with Primary Advanced Ovarian Cancer After Food and Drug Administration Approval, 8. GSK ViiV (GSK) Global Medical Affairs Director Philadelphia, PA 7d $126K-$204K Per Year (Glassdoor est.) Brain Metastases in Primary Ovarian Cancer: Real-world Data, 1. 347). Cole AL, Moretz C, Mu G, et al. Patient Profiles in Eosinophilic Granulomatosis With Polyangiitis (EGPA) ? Find a participating location at: Efficacy of Mepolizumab in Patients with Eosinophilic Granulomatosis with Polyangiitis and a Vasculitic Phenotype. Vogelmeier CF, Boucot IH, Kerwin EM, et al. Halpin DMG, Worsley S, Ismaila AS, et al. 2017;35(15):suppl TPS3113. Epidemiology of Eosinophilic Granulomatosis with Polyangiitis (EGPA) and Hypereosinophilic Syndrome (HES) in Germany: A Claims Database Study. P711; Abstract A1826]. Patient Experience Information (PEI) and Patient Involvement in Health Technology Assessment (HTA) Processes in 7 European Countries Using Immuno-Oncology Examples: How Can the Patient Voice Make an Impact? The estimated additional pay is $52,492 per year. 8. 801; Abstract A7738]. Andrews LP, Marciscano AE, Drake CG, Vignali DAA. The science of giving We are led by our purpose: to get ahead of disease together. Baseline Characteristics in Patients with Eosinophilic Granulomatosis with Polyangiitis in the U.S. A phase I study of GSK525762, a selective bromodomain (BRD) and extra terminal protein (BET) inhibitor: results from part 1 of phase I/II open label single agent study in patients with acute myeloid leukemia (AML). DREAMM-4: Evaluating Safety and Clinical Activity of Belantamab Mafodotin in Combination With Pembrolizumab in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) [Poster not available for viewing due to copyright restrictions], 14. 10. This effort supports employees by enhancing their strengths and addressing any development gaps through individual and group coaching and sponsorship. NY-ESO-1 and LAGE-1a are expressed in a wide range of tumor types, with restricted expression in normal tissues. 1. Trade marks are owned by or licensed to the GSK group of companies. POSTER: DREAMM-2: Single-Agent Belantamab Mafodotin (GSK2857916) in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) and Renal Impairment. DREAMM-5 Platform Trial: Belantamab Mafodotin (Belamaf) in Combination With 4 Different Novel Agents in Patients With Relapsed/Refractory Multiple Myeloma (RRMM), 7. Benefit?risk profiles of fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) versus UMEC/VI in patients with chronic obstructive pulmonary disease: a Markov model. Mularski RA, Drummond MB, Jain R, et al. © 2022 GSK group of companies or its licensor. POSTER: Evaluation of cCRESS in Phase 2 Randomised Placebo-controlled Study of Sequential Belimumab/Rituximab Administration in Patients with Primary Sjogren's Syndrome, 3. Infusion-Related Reactions (IRRs) in the DREAMM-2 Study of Single-Agent Belantamab Mafodotin (Belamaf) in Patients With Relapsed/Refractory Multiple Myeloma (RRMM), 5. P699; Abstract A1814]. Impact of the COVID-19 Pandemic on Dispensing of Respiratory Therapies Among Patients with Chronic Obstructive Pulmonary Disease (COPD) in the United States: A Population-Based Study. Differences in Patient Characteristics between Asthma Patients with and without Eosinophil Measurements. Cross-sectional survey to assess the burden of nocturnal symptoms in patients with chronic obstructive pulmonary disease (COPD). Das M, Zhu C, Kuchroo VK. 4. #WIW2023 #TheBigCatchUp POSTER: Thrombocytopenic Myelofibrosis Patients Previously Treated With a JAK Inhibitor in a Phase 3 Randomized Study of Momelotinib versus Danazol [MOMENTUM], 2. POSTER: Early COVID-19 Treatment With SARS-CoV-2 Neutralizing Antibody Sotrovimab. 2. Anderson M, Drummond MB, Jain R, et al. Tai Y-T, Anderson KC. Prevalence and Frequency of Eosinophil Testing in Patients with Asthma. Thompson-Leduc P, Ghaswalla P, Cheng WY, et al. Symptom Burden in Medicare Advantage Patients with COPD Initiating Umeclidinium/Vilanterol or Fluticasone Propionate/Salmeterol Therapy. 4. Singh AK, et al. real person. Mepolizumab Treatment Leads to Clinical Asthma Remission in Patients with Severe Eosinophilic Asthma: Results from the Real-World REDES Study. POSTER: Systematic literature review of prognostic factors associated with overall survival among advanced synovial sarcoma and myxoid/round cell liposarcoma subjects, 3. By bringing outstanding people together in an inclusive environment to do work that matters, we can impact the world's health. Neutrophil extracellular traps and CXCR2 antagonism in chronic obstructive pulmonary disease: A pilot randomized control study. Exploring Use of Regular ICS/LABA Dosing in Moderate to Severe Asthma Among Physicians: Results from the Asthma Patients? 1. Richards A, et al. Tabberer M, von Maltzahn R, Bacci E, et al. ORAL PRESENTATION: Primary Efficacy and Safety of letetresgene autoleucel (lete-cel; GSK3377794) Pilot study in patients with advanced and metastatic myxoid/round cell liposarcoma (MRCLS), 4. Poster No. Liu M, Bagnasco D, Matucci A, et al. 22 Gsk Medical Affairs jobs in London, England, United Kingdom (2 new) Today's top 22 Gsk Medical Affairs jobs in London, England, United Kingdom. Dasgupta, I et al. PO0465, 4. 4. POSTER: BET Inhibitor Molibresib for the Treatment of Advanced Solid Tumors: Final Results From an Open-Label Phase I/II study, 20. Patient-reported outcomes (PROs) in the GARNET trial in patients (pts) with advanced or recurrent mismatch repair deficient/microsatelite instability-high (dMMR/MSI-H) endometrial cancer (EC) treated with dostarlimab, 7. Get notified about new Gsk Medical Affairs jobs in United States. Registered office: 980 Great West Road, Brentford, Middlesex, TW8 9GS, United Kingdom. Hemoglobin Efficacy and Cardiovascular Safety Data from the ASCEND-ND, -D, and -ID Trials. POSTER: Impact of Initiation Timing of Niraparib Maintenance Treatment in Newly Diagnosed Advanced Ovarian Cancer, 6. Youll have the space to build and contribute to a high-performing team to make an impact on society. 6. Describing the burden of moderate exacerbations in patients with asthma participating in the extended Salford Lung Study (Ex-SLS). Review the package insert for important safety information. 6. 7. Kovalszki A, Wechsler M, Silver J, et al. 2. PUBLICATION ONLY: Current Treatment Efficacy for Metastatic Soft Tissue Sarcoma: A Targeted Literature Review, 27. ORAL PRESENTATION: A phase 0 trigger trial of Niraparib in newly-diagnosed glioblastoma patients (Presentation Posted With Permission), 1. ZEJULA [package insert]. P792; Abstract A5630]. We are committed to doing the right thing: our ambition is to improve the lives of billions across the world. Immunotherapy. los inconvenientes que esto te pueda causar. Discover resources and support for healthcare professionals with GSK US Medical Affairs. Baseline Characteristics in Patients with Eosinophilic Granulomatosis with Polyangiitis in the U.S. Effect of Serostatus on the Efficacy of Sotrovimab in Preventing COVID-19 Progression, 2. 2. Changes in Oral Corticosteroid (OCS) Use Following Initiation of Mepolizumab Therapy in Patients with Asthma. 2013;62(4):773-785. Identifying drivers of patients? PUBLICATION ONLY: STING Agonist GSK3745417 Induces Apoptosis, Antiproliferation, and Cell Death in a Panel of Human AML Cell Lines and Patient Samples, 1.POSTER: Efficacy and Safety of Belantamab Mafodotin Monotherapy in Patients with Relapsed or Refractory Light Chain Amyloidosis: A Phase 2 Study by the European Myeloma Network (Presentation Posted With Permission), 2. ?trap") fused via a flexible linker to the C-terminus of each heavy chain of the IgG1 antibody blocking PD-L1. Singh AK, et al. Triple checkpoint blockade targeting PD-1, TIM-3, and LAG-3 improves T cell reinvigoration and antitumor efficacy over single and double combinations, 1. CAPTAIN Study: Treatable Traits and the Outcome of Treatment with Inhaled Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Versus FF/VI Therapies in Patients with Uncontrolled Asthma, a Pre-specified Subgroup Analysis. receptor II (TGF-?RII or TGF-? preferences for treatments of anemia of chronic kidney disease: a qualitative study. Initiating Mepolizumab. [Poster No. Fiore. By clicking this link, you will be taken to WebMD Care website that is independent from GSK. 1. Pitrez P, Bruselle G, Yorganc?o?lu A, et al. Steinfeld J, Roufosse F, Kahn JE, et al. TSR-033 is a humanized LAG-3 antagonist IgG4 mAb that is being investigated as a monotherapy and in combination with anti?PD-1 therapy in advanced solid tumors. POSTER: MOMENTUM: Phase 3 Randomized Study of Momelotinib (MB) versus Danazol (DAN) in Symptomatic and Anemia Myelofibrosis (MF) Patients Previously Treated with a JAK Inhibitor (Encore), 2. This resource may include information that has not been approved by the US Food and Drug Administration. POSTER: Subramanian S, et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. Poster No. Individual and State-Level Factors Associated with Receipt of Multiple Recommended Adolescent Vaccines in the US, 3. Molfino NA, Averell CM, Hahn BA, et al. #News for #investors and #media: Today we announced the proposed acquisition of @BELLUSHealth, a clinical stage biopharmaceutical company that further strengthens our specialty medicines and respiratory pipeline. GSK Director, US Medical Affairs, Adult Immunization and Health Equity Durham, NC 30d+ $71K-$112K Per Year (Glassdoor est.) Characterization of severe asthma patients affiliated to the Hospital Italiano Medical Care Program in Buenos Aires, Argentina. Learn how to prepare, what will be collected, and how to safely store your medicine until the event at: DREAMM-2: Single-Agent Belantamab Mafodotin (Belamaf) Effects on Patient-Reported Outcome (PRO) Measures in Patients with Relapsed/Refractory Multiple Myeloma (RRMM), 2. Stability Calculator, Contact 1. ASCEND-ID: Daprodustat is non-inferior to darbepoetin alfa in treating anemia in incident dialysis patients. 2. Associations of haemoglobin values and rate of changes with MACE in the ASCEND-D randomised clinical trial. Watch the video here: gsk.to/3KQpI7P, Today is the day! Real-World Impact of Triple Therapy with Fluticasone Furoate, Umeclidinium, and Vilanterol on Asthma Control among Patients with Asthma in the US. Prevalence and Frequency of Eosinophil Testing in Patients with Asthma. 3. Herrera-Restrepo O et al. Bintrafusp alfa is a bifunctional fusion protein composed of the extracellular domain of the human transforming growth factor ? 6. Click the link in the email we sent to to verify your email address and activate your job alert. 11. PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes. CAPTAIN: Effects of age as a continuous variable on asthma control. Singh AK, et al. 1090; Abstract A3325]. takebackday.dea.govw 2018;22(4):343-351. 14. Efficacy and Safety of Mepolizumab in Hypereosinophilic Syndrome: a Phase III, Randomized, Placebo-Controlled Trial. Real-World Benefits of Mepolizumab in Patients With Severe Asthma and Comorbid GERD or Anxiety/Depression: Post Hoc Analysis ?of REALITI-A? Fedoriw A, Rajapurkar SR, O?Brien S, et al. Anti-tumor activity of the type I PRMT inhibitor, GSK3368715, synergizes with PRMT5 inhibition through MTAP loss. Fowler A, Kerstjens HAM, Bailes Z, et al. Slade D, Ray R, Moretz C, et al. [Poster No. GSK values your privacy and your trust is important to us. Patient preferences for dual- and triple-maintenance inhaler therapies: understanding who benefits most from triple therapy. 10. POSTER: Long-term protection against herpes zoster by the adjuvanted recombinant zoster vaccine: interim efficacy, immunogenicity and safety results at approximately 10 years after initial vaccination. T-cell immunoglobulin and mucin domain-3 (TIM-3), is a negative regulatory checkpoint molecule that regulates T-cell exhaustion, dampens the antitumor immune response, and may promote tumor cell migration and invasion. Rothnie K, Han X, Bancroft T, et al. 5. When expanded it provides a list of search options that will switch the search inputs to match the current selection. Analysis of a Composite Endpoint of Exacerbation and Early Study Treatment Withdrawal in Symptomatic Patients With COPD Free of Inhaled Corticosteroids: A Post Hoc Analysis of the EMAX Trial. The estimated total pay for a Medical Science Liaison at GSK is $234,850 per year. POSTER: Effectiveness and Safety of Belantamab Mafodotin in Patients with Relapsed or Refractory Multiple Myeloma in Real-Life Setting: The ALFA Study, 6. Non-clinical tumor models reveal broad combination potential of ICOS agonist antibodies, April 10-15, 2021 and May 17-21, 2021 | Virtual, 1. A Nationwide Multicentric Study, 4. Analysis of Co-Resistance Among Escherichia coli Urine Isolates From Female Outpatients in the United States. Goodall E, Wood R, Numbere B, et al. Evaluation of the Psychometric Properties, Scoring Algorithm, and Score Interpretation of the E-RS: Asthma in Two Clinical Trials of Moderate to Severe Asthma. Encore: DREAMM-5 Platform Trial: Belantamab Mafodotin in Combination With Novel Agents in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) [Poster not available for viewing due to copyright restrictions], 16. POSTER: Real-world overall survival in second-line maintenance niraparib monotherapy vs active surveillance in patients with recurrent ovarian cancer (ESGO Encore), 1. Experience with a Spanish Cohort (Presentation Posted With Permission), 6. The anti-BCMA antibody-drug conjugate belantamab mafodotin (GSK2857916) drives immunogenic cell death and immune-mediated anti-tumor response, and in combination with an OX40 agonist potentiates in vivo activity. ORAL PRESENTATION: Bone Marrow Fibrosis Changes Do Not Correlate with Efficacy Outcomes in Myelofibrosis: Analysis of More Than 300 JAK Inhibitor-Nave Patients Treated with Momelotinib or Ruxolitinib, 1.

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